The SAMPILIO X8 uses no conventional peristaltic or syringe pumps, but patented small-volume diaphragm pumps (RIGGTEK patent*). The disadvantage of a conventional sampler with peristaltic pumps is low precision and short lifetime. The problem with syringe pumps is the non-compliance with the FIFO (First In – First Out) principle, a huge dead volume or high dwell volume. This results in long sampling intervals, time inaccuracy or mixing during sampling (First In – Last Out) and a high cross-contamination. By contrast, SAMPILIO’s diaphragm pumps work precisely and maintenance-free for many years. The FIFO delivery principle with low dead volumes finally makes the dissolution analysis comparable to manual sampling! So accuracy in time and synchrony as well as minimal cross-contamination, very short sampling intervals and minimal volume loss are guaranteed!